Work in this laboratory is focussed on leishmaniasis, a chronic disease caused by the intracellular protozoa parasite Leishmania which affects more than 500 million people in several countries in the world. Our goal is to hopefully understand the survival mechanism(s) of the parasite in human macrophages (a stressful environment) during infection at the molecular level and ultimately use molecular probes for diagnostic purposes as well as design vaccine(s) for future treatment of individuals infected with this parasite.
Daifalla, S. N., Bayih, A.G. and Gedamu, L. (2012) Leishmania donovani recombinant iron superoxide dismutase B1protein in the presence of TLR-based adjuvants induces partial Protection of BALB/c mice against Leishmania major infection, Exp. Parasitol. 131: 317-24.