IT  •  MY U OF C  •  CONTACTS   
     
  Dr. Rodney Roche  
     
 

Position:

Emeritus Professor of Biochemistry and Chemistry (1994)
Faculty Professor (1994-1995)
Professor of Biochemistry and Chemistry (1987-1994)
Professor of Chemistry (1978-1987)

Qualifications:

B.Sc. Chemistry, University of Glasgow, 1957
Ph.D. Chemistry, University of Glasgow, 1965
Fellow of the Royal Society of Chemistry 1975


Phone:

(403) 247-8686

Email:

roche@ucalgary

 
     
 

Research Interests

  • The Protein Folding Problem.
  • Protein Evolution
  • Episemological issues in Evolutionary Theory

 

 
     
 

Selected publications

  • Litster, S.A., D.R. Wetmore, R.S. Roche and P.W. Codding. 1996. The Structure of the E144S Active-Site Mutant of the B. cereus Thermolysin-like Neutral Protease at 2.8Å . Resolution. Acta. Cryst., D52: 543-550.
  • Wetmore, D.R., S.-L. Wong & R.S. Roche. 1994. The efficiency of processing and secretion of the thermolysin-like neutral protease from Bacillus cereus does not require the whole prosequence, but does depend on the nature of the amino acid sequence in the region of the cleavage site. Molecular Microbiology. 12: 747-759.
  • Wetmore, D.R., S.-L. Wong and R.S. Roche. 1992. The Role of The Pro-sequence in the Processing and Secretion of the Thermolysin-like Neutral Protease from Bacillus Cereus. Molecular Microbiology. 6: 1593-1604.
  • Buchanan, J.D., R.J.T. Corbett and R.S. Roche. 1986. The Thermodynamics of Calcium Binding to Thermolysin. Biophysical Chemistry, 23: 183-199.
  • Corbett, R.J.T. and R.S. Roche. 1984. The Use of Size Exclusion Chromatography for the Study of Protein Folding and Stability. Biochemistry, 23: 1888-1894.

 

 

 

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